High-Precision Automatic Vial Filling Equipment for Aseptic Processing
Product Overview: Advanced Aseptic Filling Solutions
Our Automatic Vial Filling Equipment is engineered for the rigorous demands of global biopharmaceutical, vaccine, and high-value liquid manufacturing. Integrating high-precision dosing, rubber stoppering, and aluminum cap crimping into a seamless monoblock system, this line ensures high sterility, operational efficiency, and zero product cross-contamination.
Fully compliant with cGMP and ISO9001 standards, our equipment easily accommodates standard tubular and molded glass vials ranging from 2ml to 100ml. Designed with a compact footprint and intuitive controls, it provides a reliable, flexible solution for clinical trials and full-scale commercial manufacturing.
Technical Specifications
| Parameter | Specification |
| Applicable Container | 2ml – 100ml Glass Vials (Tubular / Molded) |
| Dosing Accuracy | ±1% (Servo Ceramic Pump / Peristaltic Pump) |
| Stoppering Type | Full-stoppering & Half-stoppering (For Lyophilization) |
| Contact Parts Material | 316L Stainless Steel & FDA-approved PTFE/Silicone |
| Non-Contact Material | 304 Stainless Steel |
| Control System | Siemens PLC with HMI Touchscreen |
Vial Filling Equipment Key Advantages & Core Features
Equipped with valveless ceramic rotary piston pumps or peristaltic pumps driven by independent servo motors, achieving ultra-high dosing accuracy (≤±1%) and zero liquid dripping.
Featuring smooth, rounded surfaces without dead angles, all fluid contact parts are made of 316L stainless steel, designed for efficient cleaning and sterilization.
Advanced vacuum-assisted stoppering technology ensures precise stopper placement for both standard liquid injectables and freeze-dried (lyophilized) formulations.
Modular components enable operators to perform rapid format adjustments between different vial sizes, significantly minimizing downtime during production switches.
How It Works: Aseptic Process Workflow
[Vial Infeed] ➔ [Nitrogen Purging (Optional)] ➔ [Servo Precision Liquid Filling] ➔ [Aluminum Cap Crimping] ➔ [Rubber Stoppering (Full/Half)] ➔ [Outfeed & Inspection]
Frequently Asked Questions (FAQ)
Q1: Can this vial filling equipment handle both liquid and lyophilized (freeze-dried) products?
A: Yes. Our machine supports both full-stoppering for standard liquid injectables and half-stoppering for vials that require freeze-drying (lyophilization) prior to final capping.
Q2: How long does a format changeover take for different vial sizes?
A: Thanks to our modular, tool-less quick-change design, operators can complete a full format changeover (e.g., from 2ml to 10ml vials) in under 30 minutes.
Q3: What filling pump options are available?
A: We offer high-precision ceramic rotary piston pumps for high accuracy and long service life, as well as peristaltic pumps for disposable single-use fluid path applications.
Q4: What validation documentation do you provide for regulatory audits?
A: We provide a comprehensive FAT/SAT protocol and full DQ, IQ, and OQ validation documentation packages to help your facility pass audits efficiently.
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