Prefilled Syringe Filling Vial Filling And Sealing Machine
Prefilled Syringe Filling Vial Filling And Sealing Machine

Prefilled Syringe Filling Vial Filling And Sealing Machine

vial filling and sealing machine is a special equipment developed by our company for aseptic filling, stoppering of vials. capping part is optional .The front end can be equipped with an ultrasonic bottle washer, a hot air circulation tunnel oven, a bottle unscrambler, etc., to achieve The continuous operation of integrated processes such as automatic bottle unpacking, automatic bottle feeding, automatic filling, automatic stoppering, and automatic capping realizes the filling and sealing of medicinal liquids. The whole machine adopts servo motor high- precision control, high degree of automation, stable and smooth operation, and is widely used in biopharmaceutical, medical beauty.
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vial filling and sealing machine

 

is a special equipment developed by our company for aseptic filling

vial filling and sealing machine

Pre-filled filling machines can realize the filling production of various products

 
Prefilled filling machines usually use an automated control system, and their working principle generally includes the following steps: the prefilled syringe or container to be filled is accurately delivered to the filling station through a conveying device; then, a precise metering pump or filling system is used to accurately inject the drug solution into the container according to the preset dose; then, nitrogen filling or other gas replacement operations may be performed to remove the air in the container to prevent drug oxidation, etc.; after that, sealing operations are performed, such as pressing the rubber stopper and rolling the aluminum cap, etc., to ensure the sealing of the container; the filled product is transported to the subsequent packaging process

Products Description

-High-precision filling: It can accurately control the filling volume with a small error range to ensure that the liquid content in each prefilled syringe is accurate, which is especially important for drugs that require accurate dosages, such as vaccines and biological agents.

 

-Highly automated: From feeding, filling, sealing to output, the entire process can be automated, which greatly improves production efficiency, reduces manual intervention, and reduces the risk of contamination and errors caused by human factors.

 

-Aseptic design: The key components and operating environment of the equipment usually adopt aseptic design, such as equipped with aseptic conveying pipelines, aseptic filling heads, and clean layer filling environments, to ensure that the drugs are not contaminated by microorganisms during the filling process.

 

-Multifunctional and adaptable: It can adapt to prefilled syringes or containers of different specifications and models. By replacing a small number of accessories or adjusting parameters, it can realize the filling production of a variety of products, with strong versatility and flexibility.

 

Technical parameter

Machine name

vial filling and sealing machine

Applicable materials

water or powder

Filling range

0.1-30ml (piston pump needs to be replaced)

Number of filling heads

1-2(customized)

Filling accuracy

±1%

Production capacity

1500-3000 pieces/hour

Pass rate of plugging

≥99.8%

Capping pass rate

≥99.8%

Working Principle

Working Principle of Syringe Filling Machine

Aseptic filling technology‌

 

Through automated control systems and aseptic operation procedures (including sterilization, filtration, filling and sealing), aseptic protection is achieved throughout the production process to ensure that materials are free from microbial contamination.

Modular system collaborative operation‌

 

It consists of a conveying system, a filling system and a sealing system: the material enters the filling system through a conveyor belt, is accurately filled into the container by gravity or screw metering, and is finally sealed by the sealing system. Some equipment integrates vacuum technology to eliminate bubble interference during the filling process.

Intelligent control‌

 

The PLC or MES system is used to monitor production parameters (such as filling volume and temperature) in real time. Some models are equipped with a visual inspection system to automatically remove unqualified products, and support data cloud storage for traceability.

Vial operation video

Customer case prefilling operation video

What should I pay attention to when using a prefilled filling machine?

-During use, relevant safety operating procedures must be followed to ensure the safety of personnel and equipment.

-It is strictly forbidden to perform any adjustments or maintenance operations that may endanger safety while the equipment is running.

-Keep the filling environment clean and sanitary to prevent dust, microorganisms, etc. from mixing into the product.

-Control the temperature and humidity of the filling room to ensure the stability and quality of the product.

-Carry out regular cleaning and maintenance to ensure the normal operation of the equipment and extend its service life.

-Replace worn parts and aging seals in time to prevent leakage and contamination.

-Strictly control the quality of raw materials to ensure that the medicines or liquids to be filled meet the relevant standards and requirements.

-During the filling process, continuously monitor the product quality and adjust the equipment parameters in time to ensure the stability of product quality.

 

Why Choose Us

Strong R&D team

Strong and stable R&D team with 15 years' experience and outstanding creativity and innovation.

Strict Quality Control

Adopt ISO clean environment design, closed filling throughout the whole process, in compliance with FDA aseptic production regulations

Certificate

CE,FDA,GMP,ISO

pre-filled filling machine

Personalized options
 designs, develops, and manufactures washing, sterilizing, filling, freeze-drying, and closing machines for vials, bottles, syringes, cartridges, and IV Bags to process liquid, semi-solid products, and powders in sterile conditions. The machines run either individually or can be integrated into a complete production line.

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One-stop syringe filling machine Factory in China

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