Name: China Dual Chamber Syringe Filling Machine Manufacturers Suppliers Factory - Made in China - ALWELL Machinery
Brand: ALWELL
SKU: 253295232

Dual Chamber Syringe Filling Machine,Dual Chamber PFS Filling and Stoppering Machine

In pharmaceutical manufacturing, the dual-chamber prefilled syringe (PFS) filling and stoppering machine is a critical piece of equipment, particularly for the production of dual-component injectable products. This system enhances production flexibility and efficiency by enabling simultaneous filling and stoppering of two distinct drug solutions within a single syringe.

Operating through high-precision automation, the machine ensures accurate dosing and maintains strict aseptic conditions throughout the process. It is equipped with advanced pumping or dosing mechanisms that deliver precise volumes of medication according to predefined parameters. All procedures are conducted in a closely controlled environment to prevent contamination and preserve product integrity.

Once filled, the syringes are automatically sealed using integrated stoppering systems that guarantee container closure integrity and sterility. The entire process is monitored under rigorous quality control protocols, with continuous verification of key metrics such as fill volume accuracy and environmental conditions. Operators can oversee production, adjust settings, and intervene as needed via an intuitive human-machine interface (HMI).

Designed for ease of cleaning and maintenance, the machine supports compliance with Good Manufacturing Practice (GMP) and relevant regulatory standards. Overall, the dual-chamber PFS filling and stoppering machine streamlines syringe manufacturing by automating critical steps while upholding stringent requirements for precision, sterility, and quality assurance. This technology is essential for pharmaceutical companies seeking reliable and efficient production of advanced injectable drug products.

Our factory

syringe filling machine factory

Provide Free Testing Raw Materials.

- Welcome to Inquiry and Cooperation

Get catalog and syringe filling solutions from the factory.

Products Description

"Traditional filling equipment cannot meet the stringent requirements of dual-chamber syringes for step-by-step filling accuracy and sterile barriers. Our fully automatic dual-chamber filling machine is designed for products that require instant mixing, such as biologics, vaccines, and adhesives, eliminating the risk of manual intervention and ensuring 100% chamber isolation."

Fully Automated, cGMP-Compliant System for Dual-Chamber Cartridges & Syringes

✅ Dual-Lane Filling：Simultaneously fills both chambers with precision (Accuracy: ±1% for liquids/powders)
✅ Aseptic ISO 5：Integrated isolator technology with RABS/closed RABS options
✅ Flexible Format：Compatible with 1mL, 2.5mL, 5mL dual-chamber syringes (glass/polymer)
✅ Speed: Up to 12,000 units/hour
✅ cGMP Ready: Full electronic batch records (EBR), 21 CFR Part 11 compliant
✅ Zero Cross-Contamination: Patented split filling nozzles with CIP/SIP

dual-chamber cartridge

Performance Features

The design, materials, manufacturing, assembly and commissioning of the dual chamber syringe filling machine are in accordance with the new GMP regulations.
This dual chamber syringe filling machine adopts servo control system to automatically complete the processes of honeycomb tray unpacking, tearing film, conveying, filling, plug feeding, plug filling and tray output. It's with electromechanical integration control, stable operation and high degree of automation.
Applications: 1ml - 20ml (according to user specifications);
Filling range of plastic pfs machine: 0.1ml-20ml
Capacity: 2000-11000 bph
Filling head: 2-10 pcs, choose according to capacity;
Various types of filling pump options: metal pump, peristaltic pump, ceramic pump;
Filling accuracy: ≤ ± 1% (depending on the characteristics of the medicine).
Pass rate ≥99.9%
Automatic removal and return of the syringe from the honeycomb tray by means of a servo system combined with a cylinder;
Fully automatic production control with intelligent testing devices at the core stations;

Technical Parameter

Parameter Category	Specific Parameter	Description
Filling Parameters	Filling Speed	The number of syringes filled per minute, such as 50 - 200 syringes/minute, which is affected by the equipment, syringe specifications, and the characteristics of the filling substances.
	Filling Precision	Expressed as a percentage or error range, and can be controlled within ±1% or with higher precision.
	Filling Dose	The filling volume range of each chamber, from several microliters to dozens of milliliters.
Equipment Size Parameters	Overall Dimensions	350018002200mm(LWH)
Applicable Syringe Parameters	Syringe Specifications	Such as 1ml, 2ml, 5ml, etc. different specifications.
	Syringe Size Range	Length 50 - 150mm, diameter 5 - 30mm, etc., depending on the equipment.
Power and Energy Consumption Parameters	Power	In kilowatts, usually 2 - 10kW.
	Voltage	Commonly 220V or 380V, etc.
Other Parameters	Degree of Automation	Fully - automatic, semi - automatic, etc.
	Control Method	PLC control, touch - screen control, etc.