How do pharmaceutical companies choose insulin filling machines?
Insulin dosage requirements are extremely high, so choose a machine with high filling accuracy. For example, the accuracy of the syringe filling machine can reach ±0.01ml or higher, to ensure that each insulin dose is accurate.
Insulin is a biological product and is susceptible to microbial contamination. Machines with a complete aseptic filling system should be selected, such as aseptic isolation technology and laminar flow purification devices, so that the filling process is carried out in a sterile environment to minimize the risk of microbial contamination.
Consider the compatibility of the filling machine for different packaging forms (such as syringes, pen syringes, vials, etc.) and insulin dosage forms (such as quick-acting, long-acting, etc.). Companies may need to flexibly switch packaging and dosage forms according to market demand, compatible with multiple forms of machinery can better adapt to change.
Due to the strict cleaning standards of insulin production, the machine should be easy to clean and disinfect. For example, the use of detachable filling parts, smooth surface, no dead corner design, facilitate automated cleaning (CIP) and steam sterilization (SIP), reduce the possibility of cross-contamination.
Choose according to the production scale of the enterprise. If it is large-scale production, it needs an efficient filling machine, which can fill thousands or even more per hour, and can run stably for a long time to reduce failure downtime.
The highly automated filling machine reduces the risk of error and contamination caused by manual operation. For example, machines with automatic feeding, filling, sealing, testing and other functions can also be seamlessly connected to the upstream and downstream production lines, improving the overall production efficiency.
Ensure that filling machines comply with relevant pharmaceutical industry standards and regulations, such as GMP (Good Manufacturing Practice for Pharmaceutical Products). Machines with relevant certifications are more guaranteed in quality and safety, and can help enterprises successfully pass the quality inspection of drug production.
Quality after-sales service is essential. Including machine installation and commissioning, operation training, regular maintenance, fault repair and other services. Good after-sales can ensure the long-term stable operation of the machine and reduce the losses caused by equipment problems.
